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semaglutide vs metformin + for Weight Loss Efficacy and safety of once-weekly

Name: semaglutide vs metformin + for Weight Loss Efficacy and safety of once-weekly
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Description

FDA labeling says short-term use (a few weeks), though many obesity specialists use it for 12 weeks or longer based on observational evidence

These presentations require clinical workup regardless of GLP-1 agonist use

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These LCACs enhance the ability of RAW264.7 cells to phagocytose lipids by upregulating macrophage receptor with collagenous structure (MARCO), thereby aggravating the accumulation of intracellular lipids, which promotes the formation of foam cells and accelerates the development of atherosclerosis [228]

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